Modern agriculture is undermined by soil dysbiosis, the imbalance in microbial community function that is detrimental to nutrient cycling, carbon retention, and plant resilience, resulting in costly fertilizer use and poor yields. BioBead is a biodegradable hydrogel soil amendment that reverses soil dysbiosis by delivering protected fungal-bacterial consortia directly to plant roots, improving soil quality and yields.

Commercial airline pilots operate in high-stress, safety-critical environments, yet many mental-wellbeing resources remain underutilized due to stigma, concerns about career impact, and uncertainty around confidentiality—barriers that can undermine mental health, crew performance, and system resilience over time. CRMSON’s Resilience Coach, built by pilots for pilots, delivers brief, evidence-informed micro-interventions that strengthen emotional intelligence, psychological resilience, and interpersonal communication, serving as a stigma-reducing bridge to peer support and an aviation-specific human-performance resource grounded in human-centered design and human factors – delivering support before stress becomes impairment and before silence becomes a safety issue.

The EuNova Spacer is a minimally invasive, bioabsorbable device designed to restore ear pressure regulation while reducing unwanted sound transmission. Unlike existing treatments that address only one aspect of eustachian tube dysfunction, EuNova targets the underlying functional imbalance responsible for persistent symptoms.

Activated carbon is the last line of defense to remove PFAS “forever chemicals” in drinking water that have been linked to a range of illnesses including cancers, decreased vaccine response, and low birth weight in infants. Unfortunately, activated carbon is ineffective at removing many types of PFAS that are increasingly detected in drinking water sources. To overcome this limitation, we have developed PFASPure, a modified activated carbon that effectively removes a wide range of PFAS from water offering greater protection from PFAS exposure. Our technology is based on a widely used and trusted water treatment technology to allow for easy adoption by existing activated carbon users.

More than 15 million Americans live with schizophrenia, bipolar disorder, or related conditions, and during high-risk periods, their suicide rates exceed the global average by more than one hundredfold. Unfortunately, while effective treatments exist, community mental health centers are operating beyond their clinical capacity leading to warning signs often being missed that could have adverted tragedy. AI for Serious Mental Health is a platform that transforms standard brief patient self-assessments into real-time clinical insights allowing early signs of deterioration to be identified so clinicians can effectively intervene to prevent tragedy.

Potent cytokine immunotherapies are promising treatments for cancers but are often not safe to use due to severe off-target toxicity. Escher Therapeutics has developed a bacterial strain that can colonize solid tumors and secrete cytokines, enabling localized delivery of anti-tumor therapies with minimal off-target toxicity.

Despite the fact that clinicians’ patient communication skills directly impact reimbursements, medical outcomes, insurance costs, and malpractice risk profiles, there is virtually no communication assessment and coaching for clinicians once they complete their medical education and training. LarryAI provides clinicians with continuous and effective communication coaching using routinely collected conversation transcriptions combined with an AI coach based on UW’s well-recognized Patient Centered Observation Form developed by Professor Emeritus of Family Medicine Larry Mauksch and his research teams, to improve patient satisfaction, reduce clinician burnout, and improve the quality of medical care.

Early-stage drug discovery is slow, expensive, and largely unsuccessful because it is a one-at-a-time effort that begins with a single protein target that then requires a custom assay and then a screen of thousands to millions of molecules to find a lead. We have developed a new experimental platform technology, LABEL-seq, that enables hundreds of target proteins to be screened against thousands or millions of compounds simultaneously in living cells, providing biologically accurate data at a fraction of the time and cost.

Many applications, such as heavy equipment, require high power output that conventional Li-ion batteries, optimized for EVs and consumer electronics, cannot deliver due to low ion conductivity. JanuTech has developed proprietary Sb₂S₃ nanoparticles that can be added to existing battery chemistries to enable high ion conductivity and high-power output needed in applications from heavy vehicles to high-speed drones.

Leaks in compressed air and industrial gas systems represent one of the largest sources of hidden energy waste in industrial operations, with leakage losses routinely exceeding 20–30% of total consumed gas. GASLEAD is a real-time, autonomous sensor network system that monitors compressed gas lines through simple accelerometer hardware and machine-learning based anomaly detection, which allows facilities to find leaks fast and save money.

Current AI assistants produce subpar results because they don’t really know all the facets of your life due to key data and context residing across separate apps, with business travel being a case in point of hours of wasted time and non-optimal results coordinating across work, family, and health using 4-7 disconnected apps. Aria is an AI assistant that creates multiple specialized “Sims” that continuously evolve offline, learning nuanced patterns and understanding how professional ambitions interact with family commitments to create optimal and highly personalized solutions, including travel plans, with the minimum of time.