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Participants of the NW Hub I-Corps @ UW – Summer & Fall 2025

Written by CoMotion Staff / August 31, 2025

Summer 2025

Dendrimer Nanomedicine for TBI | We have developed a simple and effective nanoparticle-based system that can deliver medicine directly to neurons in the brain, even across the protective blood-brain barrier. This system uses a sugar-modified carrier to find and enter the right brain cells at the site of injury, making treatment more precise. Our method is easy to reproduce and scalable, offering a promising path for future brain disease therapies.

DeNovoAgonists | Native growth factors and cytokines have limited clinical success due to poor stability and high promiscuity. Our platform technology produces protein-based agonists that are highly stable, active, and specific for their targets, with promising studies in cells and mice. We will explore their applications in treating diseases that currently lack effective therapies while developing new agonists using our platform.

Error Disclosure Simulator | Our software is an interactive AI conversational agent that simulates realistic patient responses to a physician disclosing a harmful medical error. Using speech-to-text and text-to-speech technology, the AI interface allows users to speak naturally with a simulated patient drawn from a case library or a custom-built scenario. The AI model evaluates communication skills and provides real-time, personalized recommendations to improve empathy, information sharing, and overall disclosure efficacy.

Godel EdgeAI | Godel Space provides AI-native platforms deployed on satellites and edge devices to rapidly convert satellite imagery into actionable insights. Our solution supports applications such as post-disaster monitoring, infrastructure resilience, and defense intelligence. The technology leverages advanced foundation models and edge computing to deliver real-time situational awareness.

InnoMat.AI | InnoMat.AI is an AI-powered platform revolutionizing materials innovation by integrating material discovery, behavior simulation, and supplier intelligence into a seamless digital experience. Our solution enables R&D and supply chain teams to identify optimal materials, simulate performance virtually, and connect with verified suppliers—all within one cloud-native environment. Built on Microsoft Azure, our platform reduces prototyping costs, accelerates time-to-market, and ensures technical rigor across the innovation lifecycle.

Microvia | Bacteria offer a promising, cost-effective alternative to human live-cell cancer immunotherapies due to their ability to colonize tumors and thrive in the tumor microenvironment. We are engineering a nonpathogenic E. coli strain that can detect solid tumors and secrete therapeutic payloads for immunotherapy.

Mini MMG | Caregivers of patients receiving neuromuscular blocking drugs need a low-cost, effective way to measure the level of neuromuscular block to detect residual blockade, especially in institutions that cannot afford existing solutions. We have developed a device that measures the level of neuromuscular blockade by detecting the force exerted by the abductor pollicis brevis muscle in response to ulnar nerve stimulation. This device will help caregivers accurately monitor and manage neuromuscular block levels.

pHastCam | Our solution uses low-cost components, including a 3D-printed integrating sphere with LED lights, pH sensors created from a pH-sensitive dye, and a smartphone camera to analyze blood pH. Current blood pH devices are expensive and often inaccessible, yet blood pH is an important indicator of complications during birth in infants. Our design combines software-based image analysis with digital number evaluation to determine pH efficiently and affordably.

TheraGland | We create human iPSC-derived salivary gland organoids that are highly scalable and easily modified to model disease conditions. This system is ideal for high-throughput pharmaceutical screening to test therapeutic efficacy in treating salivary gland disease and to identify potential side effects of pharmaceuticals on salivary function.

Therapeutic Bubble Tea | Thera-T bubbles act like mobile, compartmentalized “mini-dialysis machines” that can be safely ingested. They move through the GI tract using natural peristalsis while reducing toxin concentrations and are excreted safely from the body, eliminating the need for invasive dialysis devices. Delivering these hydrogels in a patient-friendly bubble tea drink offers a less physically and psychologically draining alternative to traditional dialysis treatments.

Treatment of Overuse Injuries | We address two main challenges for patients with lower-limb overuse injuries: extended recovery time and re-injury upon returning to activity. Our innovation is an auto-adjusting brace that treats injuries while patients go about daily activities, monitors key biomechanical metrics, and enables telehealth communication for remote brace adjustments. Integrating this technology into clinical practice reduces costs and improves outcomes compared to current standards of care.

UWave Radio FM Expansion | The “UWave Radio FM Expansion Project” will add a low-power FM signal at 105.7 FM in Bothell to our existing internet radio station. Students successfully obtained this frequency from the Federal Communications Commission (FCC) in 2024. This project provides UW Bothell with a unique opportunity to create a community-building platform and enhance student-led communication through an expanded radio presence.

Vitalink | Vitalink is a wearable vital sign monitor that measures and characterizes multiple parameters, triggering tiered alarms based on different stages of patient distress that may occur during various activities.

Zukan Studio | Zukan Studio provides high-quality scientific illustrations, as well as animated and interactive digital graphics and websites for researchers and laboratories. These visual assets can be used for publications, posters, and presentations throughout the research lifecycle, helping clients effectively communicate and showcase their work.

Fall 2025

More info coming soon!